产品货号：
Z38441
中文名称：
GRAP2 Purified抗体
英文名称：
Anti-GRAP2 Purified Antibody (Clone#UW40)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GRAP2 Purified Antibody (Clone#UW40) |
| 指标别名 | Adapter protein GRID;GADS;GRAP 2;GRAP2;GRB 2 like protein;GRB2 related adapter protein 2;GRB2 related adaptor protein 2;GRB2L;GRBLG;GrbX;Grf 40;Grf40;Grf40 adapter protein;GRID;GRPL;Mona;Protein GADS;SH3 SH2 SH3 adapter Mona |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,WB |
| 基因名称 | GRAP2 |
| 克隆号 | UW40 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | GST-fusion human GRAP2/GADS protein.The mouse monoclonal antibody UW40 recognizes GRAP2/GADS,a 41kDa cytoplasmic adaptor protein that plays a pivotal role during the early events of signal transduction in T cells. |
| 计算分子量 | 38kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | GRAP2/GADS (Grb2-related adaptor protein 2/Grb2-related adaptor downstream of Shc) is a cytoplasmic adaptor protein containing N- and C-terminal SH3 domains flanking a central SH2 domain and a proline/glutamine-rich region.It is expressed predominantly in lymphoid tissue and hematopoietic cells,particularly in T cells.GRAP2/GADS plays a pivotal role during the early events of T cell signal transduction by recruiting the adaptor protein SLP-76 and its associated molecules,such as Vav,Nck,Itk,and ADAP,to the transmembrane adaptor protein LAT.GRAP2/GADS also binds several other signaling proteins,namely Gab2,HPK1 (hematopoietic progenitor kinase 1),and Cbl.Unlike similar adaptor protein Grb2,GRAP2/GADS shows higher selectivity when binding to the particular phosphorylated tyrosines of LAT adaptor. |
| Uniprot ID | O75791 |
| 基因名全称 | GRB2 related adaptor protein 2 |
| 蛋白名全称 | GRB2-related adapter protein 2 |
| 推荐稀释比 | Flow cytometry:2～6μg/mL.Intracellular staining. |
相关搜索：GRAP2 Purified抗体，GRAP2 Purified单抗，Anti-GRAP2 Purified Antibody (Clone#UW40)